{"id":22867,"date":"2026-10-13T11:48:59","date_gmt":"2026-10-13T08:48:59","guid":{"rendered":"https:\/\/atauni.edu.tr\/tip-fakultesi\/?p=22867"},"modified":"2026-10-13T11:49:36","modified_gmt":"2026-10-13T08:49:36","slug":"ataturk-universitesinden-dunya-tip-literaturune-guclu-imza-bes-yillik-arastirma-nature-communicationsta","status":"publish","type":"post","link":"https:\/\/atauni.edu.tr\/tip-fakultesi\/2026\/haberler\/ataturk-universitesinden-dunya-tip-literaturune-guclu-imza-bes-yillik-arastirma-nature-communicationsta\/","title":{"rendered":"Atat\u00fcrk \u00dcniversitesinden D\u00fcnya T\u0131p Literat\u00fcr\u00fcne G\u00fc\u00e7l\u00fc \u0130mza: Be\u015f Y\u0131ll\u0131k Ara\u015ft\u0131rma Nature Communications\u2019ta"},"content":{"rendered":"\t\t
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Atat\u00fcrk \u00dcniversitesi T\u0131p Fak\u00fcltesinin \u00f6nc\u00fcl\u00fc\u011f\u00fcnde farkl\u0131 t\u0131p disiplinlerinden ara\u015ft\u0131rmac\u0131lar\u0131n kat\u0131l\u0131m\u0131yla be\u015f y\u0131ld\u0131r s\u00fcrd\u00fcr\u00fclen kapsaml\u0131 bilimsel \u00e7al\u0131\u015fma etki fakt\u00f6r\u00fc 18 olan ve d\u00fcnyan\u0131n en prestijli multidisipliner bilim dergilerinden olan Nature Communications\u2019ta yay\u0131mland\u0131. Ara\u015ft\u0131rma, 98 farkl\u0131 sa\u011fl\u0131k durumuna sahip 4.444 bireyin molek\u00fcler verilerini bir araya getirerek hastal\u0131klar\u0131n kandaki genetik izlerini ortaya koydu.<\/p>

Atat\u00fcrk \u00dcniversitesi T\u0131p Fak\u00fcltesinden 81, Di\u015f Hekimli\u011fi Fak\u00fcltesinden 3 olmak \u00fczere toplam 84 ara\u015ft\u0131rmac\u0131n\u0131n katk\u0131 sundu\u011fu d\u00f6rt y\u0131ll\u0131k kapsaml\u0131 \u00e7al\u0131\u015fma uluslararas\u0131 bilimsel i\u015f birli\u011finin ve disiplinler aras\u0131 ara\u015ft\u0131rma k\u00fclt\u00fcr\u00fcn\u00fcn \u00f6nemli bir \u00f6rne\u011fini olu\u015fturdu.<\/p>

2021 y\u0131l\u0131nda Atat\u00fcrk \u00dcniversitesi Klinik Ara\u015ft\u0131rmalar Etik Kurulundan al\u0131nan onay\u0131n ard\u0131ndan ba\u015flayan ara\u015ft\u0131rma T\u0131p Fak\u00fcltesinin farkl\u0131 klinik ve temel bilim anabilim dallar\u0131ndan akademisyenlerin kat\u0131l\u0131m\u0131yla yakla\u015f\u0131k 5 y\u0131l boyunca s\u00fcrd\u00fcr\u00fcld\u00fc. \u00dcniversitenin g\u00fc\u00e7l\u00fc klinik ara\u015ft\u0131rma altyap\u0131s\u0131n\u0131 uluslararas\u0131 bilimsel i\u015f birlikleriyle bulu\u015fturan \u00e7al\u0131\u015fma insan hastal\u0131klar\u0131n\u0131n molek\u00fcler d\u00fczeyde anla\u015f\u0131lmas\u0131na y\u00f6nelik kapsaml\u0131 bir veri kayna\u011f\u0131 olu\u015fturdu.<\/p>

Whole Blood Transcriptomics Atlas Across Human Diseases ba\u015fl\u0131kl\u0131 ara\u015ft\u0131rman\u0131n Atat\u00fcrk \u00dcniversitesindeki koordinasyonu T\u0131bbi Genetik Anabilim Dal\u0131ndan Prof. Dr. Abdulgani Tatar ve Do\u00e7. Dr. \u00c7i\u011fdem Y\u00fcce Kahraman ile T\u0131bbi Biyoloji Anabilim Dal\u0131ndan Prof. Dr. Hasan T\u00fcrkez taraf\u0131ndan y\u00fcr\u00fct\u00fcld\u00fc.<\/p>

Tek Bir Kan \u00d6rne\u011finden Hastal\u0131klar\u0131n Molek\u00fcler D\u00fcnyas\u0131na<\/strong><\/p>

Kanserden Alzheimer ve Parkinson hastal\u0131klar\u0131na, diyabetten kalp-damar ve ba\u011f\u0131\u015f\u0131kl\u0131k sistemi hastal\u0131klar\u0131na kadar 98 farkl\u0131 sa\u011fl\u0131k durumunun incelendi\u011fi bu kapsaml\u0131 ara\u015ft\u0131rmada 4.444 bireyin tam kan gen ekspresyon profilleri analiz edildi. Hastal\u0131klara \u00f6zg\u00fc molek\u00fcler imzalar, ba\u011f\u0131\u015f\u0131kl\u0131k sistemi de\u011fi\u015fimleri ve metabolik yolaklar ayr\u0131nt\u0131l\u0131 bi\u00e7imde haritaland\u0131r\u0131ld\u0131.<\/p>

Ara\u015ft\u0131rman\u0131n bir di\u011fer \u00f6nemli a\u015famas\u0131nda 1.280 bireye ait protein verileri gen ekspresyon sonu\u00e7lar\u0131yla b\u00fct\u00fcnle\u015ftirildi. Makine \u00f6\u011frenmesi algoritmalar\u0131yla geli\u015ftirilen modeller farkl\u0131 hastal\u0131klar\u0131n molek\u00fcler \u00f6zelliklerine g\u00f6re s\u0131n\u0131fland\u0131r\u0131lmas\u0131nda \u00e7oklu omik analizlerin \u00fcst\u00fcnl\u00fc\u011f\u00fcn\u00fc ortaya koydu.<\/p>

\u00c7al\u0131\u015fman\u0131n en \u00f6nemli kazan\u0131mlar\u0131ndan biri, hastal\u0131klar\u0131n yaln\u0131zca klinik belirtilerle de\u011fil, kanda bulunan molek\u00fcler de\u011fi\u015fimler \u00fczerinden de kapsaml\u0131 bi\u00e7imde de\u011ferlendirilebilece\u011fini g\u00f6stermesi oldu.<\/p>

Elde edilen bulgular; hastal\u0131klar\u0131n erken tan\u0131s\u0131na y\u00f6nelik biyobelirte\u00e7lerin ke\u015ffi, bireye \u00f6zg\u00fc risk de\u011ferlendirmesi, hastal\u0131k s\u00fcre\u00e7lerinin izlenmesi ve ki\u015fiselle\u015ftirilmi\u015f tedavi yakla\u015f\u0131mlar\u0131n\u0131n geli\u015ftirilmesi i\u00e7in yeni ara\u015ft\u0131rma olanaklar\u0131 sunuyor.<\/p>

Nature Portfolio b\u00fcnyesinde yay\u0131mlanan ve d\u00fcnyan\u0131n \u00f6nde gelen bilim dergileri aras\u0131nda yer alan Nature Communications<\/em>\u2019ta kabul edilen bu ara\u015ft\u0131rma Atat\u00fcrk \u00dcniversitesinin uluslararas\u0131 bilim d\u00fcnyas\u0131ndaki g\u00f6r\u00fcn\u00fcrl\u00fc\u011f\u00fcn\u00fc g\u00fc\u00e7lendirirken, \u00fcniversitenin farkl\u0131 t\u0131p disiplinlerini ortak bir bilimsel hedef etraf\u0131nda bulu\u015fturabilme kapasitesini de ortaya koyuyor.<\/p>

Be\u015f y\u0131ll\u0131k bilimsel eme\u011fin \u00fcr\u00fcn\u00fc olan \u00e7al\u0131\u015fma Atat\u00fcrk \u00dcniversitesinden d\u00fcnya t\u0131bb\u0131n\u0131n gelece\u011fine uzanan \u00f6nemli bir katk\u0131 olarak bilim literat\u00fcr\u00fcndeki yerini al\u0131yor.<\/p>

Rekt\u00f6r Prof. Dr. Ahmet Hac\u0131m\u00fcft\u00fco\u011flu\u2019ndan Ara\u015ft\u0131rma Ekibine Tebrik<\/strong><\/p>

\u00dcniversitemizin farkl\u0131 t\u0131p disiplinlerinden akademisyenlerinin be\u015f y\u0131l boyunca b\u00fcy\u00fck bir \u00f6zveriyle y\u00fcr\u00fctt\u00fc\u011f\u00fc bu kapsaml\u0131 ara\u015ft\u0131rman\u0131n d\u00fcnyan\u0131n en sayg\u0131n bilim dergilerinden Nature Communications\u2019ta yer almas\u0131 bizler i\u00e7in \u00f6nemli bir gurur vesilesidir.<\/p>

Bu ba\u015far\u0131, g\u00fc\u00e7l\u00fc klinik altyap\u0131m\u0131z\u0131n, disiplinler aras\u0131 ara\u015ft\u0131rma k\u00fclt\u00fcr\u00fcm\u00fcz\u00fcn ve uluslararas\u0131 bilimsel i\u015f birliklerimizin somut bir sonucudur. Atat\u00fcrk \u00dcniversitesi olarak yaln\u0131zca bilimsel bilgi \u00fcretmeyi de\u011fil bu bilgiyi insan sa\u011fl\u0131\u011f\u0131n\u0131n gelece\u011fine katk\u0131 sa\u011flayacak evrensel bir de\u011fere d\u00f6n\u00fc\u015ft\u00fcrmeyi hedefliyoruz.<\/p>

Ba\u015fta \u00e7al\u0131\u015fman\u0131n koordinasyonunu \u00fcstlenen akademisyenlerimiz olmak \u00fczere ara\u015ft\u0131rmaya katk\u0131 sunan t\u00fcm bilim insanlar\u0131m\u0131z\u0131 g\u00f6n\u00fclden tebrik ediyor, \u00fcniversitemizin ad\u0131n\u0131 uluslararas\u0131 bilim d\u00fcnyas\u0131nda ba\u015far\u0131yla temsil eden bu k\u0131ymetli \u00e7al\u0131\u015fman\u0131n yeni bilimsel geli\u015fmelere \u00f6nc\u00fcl\u00fck etmesini diliyorum.<\/p>

Makale:<\/strong> Whole Blood Transcriptomics Atlas Across Human Diseases<\/p>

Dergi:<\/strong> Nature Communications (2026)<\/p>

DOI:<\/strong> https:\/\/doi.org\/10.1038\/s41467-026-78440-w<\/a><\/p>

\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Atat\u00fcrk \u00dcniversitesi T\u0131p Fak\u00fcltesinin \u00f6nc\u00fcl\u00fc\u011f\u00fcnde farkl\u0131 t\u0131p disiplinlerinden ara\u015ft\u0131rmac\u0131lar\u0131n kat\u0131l\u0131m\u0131yla be\u015f y\u0131ld\u0131r s\u00fcrd\u00fcr\u00fclen kapsaml\u0131 bilimsel \u00e7al\u0131\u015fma etki fakt\u00f6r\u00fc 18 olan ve d\u00fcnyan\u0131n en prestijli multidisipliner bilim dergilerinden olan Nature Communications\u2019ta yay\u0131mland\u0131. Ara\u015ft\u0131rma, 98 farkl\u0131 sa\u011fl\u0131k durumuna sahip 4.444 bireyin molek\u00fcler verilerini bir araya getirerek hastal\u0131klar\u0131n kandaki genetik izlerini ortaya koydu. Atat\u00fcrk \u00dcniversitesi T\u0131p Fak\u00fcltesinden 81, […]<\/p>\n","protected":false},"author":687,"featured_media":22868,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-22867","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-haberler"],"_links":{"self":[{"href":"https:\/\/atauni.edu.tr\/tip-fakultesi\/wp-json\/wp\/v2\/posts\/22867","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/atauni.edu.tr\/tip-fakultesi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/atauni.edu.tr\/tip-fakultesi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/atauni.edu.tr\/tip-fakultesi\/wp-json\/wp\/v2\/users\/687"}],"replies":[{"embeddable":true,"href":"https:\/\/atauni.edu.tr\/tip-fakultesi\/wp-json\/wp\/v2\/comments?post=22867"}],"version-history":[{"count":4,"href":"https:\/\/atauni.edu.tr\/tip-fakultesi\/wp-json\/wp\/v2\/posts\/22867\/revisions"}],"predecessor-version":[{"id":22872,"href":"https:\/\/atauni.edu.tr\/tip-fakultesi\/wp-json\/wp\/v2\/posts\/22867\/revisions\/22872"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/atauni.edu.tr\/tip-fakultesi\/wp-json\/wp\/v2\/media\/22868"}],"wp:attachment":[{"href":"https:\/\/atauni.edu.tr\/tip-fakultesi\/wp-json\/wp\/v2\/media?parent=22867"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/atauni.edu.tr\/tip-fakultesi\/wp-json\/wp\/v2\/categories?post=22867"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/atauni.edu.tr\/tip-fakultesi\/wp-json\/wp\/v2\/tags?post=22867"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}